The shark struck in waters around 300 yards off Newcomb Hollow Beach in Wellfleet at 2:25pm local time (7.:25pm GMT) on Saturday.
A man who was bitten by a shark at a Wellfleet beach today has died, according to police.
"The Town of Wellfleet is heartbroken by this tragedy", town administrator Dan Hoort and Wellfleet Selectboard chair Janet Reinhart said in a statement.
Speaking to WBUR, local fisherman and surfer Joe Booth witnessed the attack and said Medici could be seen aggressively kicking something behind him when the flicker of a shark tail could be seen in the water. He realized what was happening when the friend came to shore, dragging his injured friend.
The beach where Medici was boogie boarding has a sign warning of the potential dangers of the water that urges swimmers to "Be Shark Smart".
Just last month, a 61-year-old man suffered puncture wounds following another Cape Cod shark attack.
Cape and Islands District Attorney Tara Militmore named Mr Medici has the man who had died.
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It's not clear what type of shark was involved in the attack.
Booth said others on the beach attempted to make a tourniquet while others called 911.
"Shark attacks don't happen as often, there has only just been a recent rise in incidents", Chris Hargrove, who is the special officer for Cape Cod National Seashore, told NBC News. He is recovering from serious injuries in a Boston hospital.
News Release from County Commissioner Ronald Beaty, published verbatim.
Police and rescue vehicles fill the parking lot at Newcomb Hollow Beach in Wellfleet, Mass., Saturday, Sept. 15, 2018, after a man was fatally attacked by a shark. "Right spot, wrong time, I guess".
The Cape Cod National Park Service revealed that around 12:30pm, Medici was knocked off his board while in the waters and was then attacked by the shark. Great White Sharks are predators and should be considered unsafe.
The state's last shark attack fatality was on July 25, 1936, when 16-year-old Joseph Troy Jr. was bitten in waters off Mattapoisett.