Liverpool is also trying to overcome a 3-0 first-leg deficit without forward Robert Firmino, who has a muscle injury.
Now, the task in hand for the Reds is to try and overturn that three-goal disadvantage without conceding an away goal.
Now, if Liverpool are to reach a second consecutive Champions League final, they will have to repeat that feat against the Catalan giants at Anfield on Tuesday night. "He's desperate (to play)".
"Both of them [Salah and Firmino] are unavailable for tomorrow", Klopp said at his prematch news conference at Anfield.
A draw would only bring Liverpool level with Manchester City in the Premier League table with one game left to play, while Manchester City has two league fixtures left against Leicester City and 17th-place Brighton.
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They had their chances in the first half at the Vitality Stadium, but found debutant goalkeeper Mark Travers in inspired form. Eddie Howe told Sky Sports Bournemouth's summer business will be their biggest yet as they look to improve for next season.
"It's not a precaution, it's a concussion", said Klopp.
Twelve months ago, Liverpool faced AS Roma at this stage of last year's competition - after the Italian side had knocked out Barcelona in the quarterfinal.
Origi, who also scored a 96th-minute victor to beat Everton in the Merseyside derby in December, Shaqiri and Daniel Sturridge have made important contributions in a supporting role to a club record points tally for Liverpool this season. Creating an atmosphere, using that atmosphere and celebrate the situation with good football and create a football party.
"I imagine the place will be rocking before we score. When you're on the bench, you are an option to play".
"We know about how big the challenge is, but this team is so wonderful".
While Barca's commanding lead puts them in pole position to reach the final, their stunning exit against Roma at the quarter-final stage previous year - when they surrendered a three-goal advantage on Italian soil - remains fresh in their minds.